Endocrine Abstracts

We previously showed that GH administration to rats with induced brain injury produces a clear proliferation of neural precursors within DG and a significant reduction of apoptosis. In this study, we tried to delineate, in vitro, the signaling pathways by which GH produces these effects on neurogenesis.Methods: Neural stem cells were obtained from the Subgranular Zone of 9 days old mice and then plated on petri dishes under proliferation condition...